Introduction to Sex as a Biological Variable and the Video Series

Duration: 7:10
Annotated Script

A brief history of the NIH Policy on the inclusion of sex as a biological variable and introduction to the purpose of the video series.


Sex Differences in Hippocampal Structural and Synaptic Plasticity: Implications for Normal Learning and Memory

Duration: 14:03
Annotated Script 

Learn the basics of sex differences in hippocampal structural and synaptic plasticity, with particular attention to how biological sex influences neurogenesis, dendritic morphology, and long-term potentiation.


Sex Hormone Synthesis and Mechanism of Action

Duration: 6:38
Annotated Script 

Learn about the synthesis and mechanism of action of sex hormones and how they can change behavioral responses using fear learning and generalization as an example.


Sex Differences during Normal Aging and Pathological Aging

Duration: 7:56
Annotated Script 

Learn about sex differences during normal and pathological aging, using Alzheimer’s disease as an example.


Sex Differences in Stress Reactivity and its Implications for Neuropsychiatric Diseases

Duration: 12:21
Annotated Script 

Learn about sex differences in behavioral and neurological responses to different types of stressors, with a focus on the role of the HPA axis, and how stress reactivity differences may mediate observed differences in the prevalence of neuropsychiatric diseases.


Sex Differences in Adult Social Behavior

Duration: 7:00
Annotated Script 

Learn about known sex differences in social behaviors, focusing on social recognition, social learning and aggression.