1

Introduction to Sex as a Biological Variable and the Video Series

Duration: 7:10
Annotated Script

A brief history of the NIH Policy on the inclusion of sex as a biological variable and introduction to the purpose of the video series.

2

Sex Differences in Hippocampal Structural and Synaptic Plasticity: Implications for Normal Learning and Memory

Duration: 14:03
Annotated Script 

Learn the basics of sex differences in hippocampal structural and synaptic plasticity, with particular attention to how biological sex influences neurogenesis, dendritic morphology, and long-term potentiation.

3

Sex Hormone Synthesis and Mechanism of Action

Duration: 6:38
Annotated Script 

Learn about the synthesis and mechanism of action of sex hormones and how they can change behavioral responses using fear learning and generalization as an example.

4

Sex Differences during Normal Aging and Pathological Aging

Duration: 7:56
Annotated Script 

Learn about sex differences during normal and pathological aging, using Alzheimer’s disease as an example.

5

Sex Differences in Stress Reactivity and its Implications for Neuropsychiatric Diseases

Duration: 12:21
Annotated Script 

Learn about sex differences in behavioral and neurological responses to different types of stressors, with a focus on the role of the HPA axis, and how stress reactivity differences may mediate observed differences in the prevalence of neuropsychiatric diseases.

6

Sex Differences in Adult Social Behavior

Duration: 7:00
Annotated Script 

Learn about known sex differences in social behaviors, focusing on social recognition, social learning and aggression.