1

    Introduction to Sex as a Biological Variable and the Video Series

    Duration: 7:10
    Annotated Script

    A brief history of the NIH Policy on the inclusion of sex as a biological variable and introduction to the purpose of the video series.

    2

    Sex Differences in Hippocampal Structural and Synaptic Plasticity: Implications for Normal Learning and Memory

    Duration: 14:03
    Annotated Script 

    Learn the basics of sex differences in hippocampal structural and synaptic plasticity, with particular attention to how biological sex influences neurogenesis, dendritic morphology, and long-term potentiation.

    3

    Sex Hormone Synthesis and Mechanism of Action

    Duration: 6:38
    Annotated Script 

    Learn about the synthesis and mechanism of action of sex hormones and how they can change behavioral responses using fear learning and generalization as an example.

    4

    Sex Differences during Normal Aging and Pathological Aging

    Duration: 7:56
    Annotated Script 

    Learn about sex differences during normal and pathological aging, using Alzheimer’s disease as an example.

    5

    Sex Differences in Stress Reactivity and its Implications for Neuropsychiatric Diseases

    Duration: 12:21
    Annotated Script 

    Learn about sex differences in behavioral and neurological responses to different types of stressors, with a focus on the role of the HPA axis, and how stress reactivity differences may mediate observed differences in the prevalence of neuropsychiatric diseases.

    6

    Sex Differences in Adult Social Behavior

    Duration: 7:00
    Annotated Script 

    Learn about known sex differences in social behaviors, focusing on social recognition, social learning and aggression.

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